Laboratory testing services

Determination of the specific migration of elements listed in Annex II of Commission Regulation (EU) No 2020/1245 (15th amendment of the Commission Regulation (EU) No 10/2011). The Annex lists the following elements and specific migration limits (SMLs) for each element: Element Symbol SML [mg/kg] Cadmium Cd Not detectable (LOD 0.002) Arsenic As Not detectable (LOD 0.01) Lead Pb Not detectable (LOD 0.01) Mercury Hg Not detectable (LOD 0.01) Chromium Cr Not detectable (LOD 0.01) Nickel Ni 0.02 Antimony Sb 0.04 Cobalt Co 0.05 Europium Eu 0.05 (sum) Gadolinium Gd Lanthanum La Terbium Tb Lithium Li 0.6 Manganese Mn 0.6 Aluminium Al 1 Barium Ba 1 Copper Cu 5 Zinc Zn 5 Iron Fe 48 Calcium Ca - Magnesium Mg - Potassium K - Sodium Na - The service is available with all conventional food simulants: Water-based simulants: water, 3% acetic acid, 10% ethanol, 20% ethanol, 50% ethanol (simulants A, B, C, and D1), Solvent simulants: 95% ethanol, isooctane (simulants D2e and D2i), Vegetable oil (simulant D2), Tenax adsorbent (simulant E). The cost of the analysis depends on the number of samples, the desired scope of testing, and the food simulant used.

Targeted screening and quantification of PFAS compounds in various materials with accredited in-house LC-MS/MS methods. Number of substances covered by the method 77 substances analyzed, 126 substances listed (salts of analyzed acids, alcohols, etc.), Total of 203 substances reported, A list of substances is provided in a separate appendix together with the quotation. Examples of target analytes include PFOS, PFOA, PFHxS, and PFNA. The full list of compounds is available upon request. In addition to plastic and paper, the measurement is suitable for textiles, leather, wood, metals, paints, and coatings. One common application of this analysis is evaluating compliance with EU and US regulations on PFAS in food packaging. If this is the goal, a total (organic) fluorine (TOF) analysis should be conducted in addition to the targeted screening. We are happy to provide a single offer that includes both analyses.

We offer several accredited methods for determining the total fluorine (TF) content of combustible materials: EN 14582, based on combustion ion chromatography (CIC). The method is recommended by the Nordic Council of Ministers as a quick and powerful total fluorine screening technique., EN 15408 using oxygen bomb combustion treatment followed by ion chromatography (IC). This method can be applied to plastic sheets and granules, and it is also possible to determine the total content of S, Cl, and Br., ASTM D7359-23, based on oxidative pyrohydrolytic combustion, followed by CIC.. The most suitable method is typically selected based on the sample matrix. However, please let us know if you wish a specific standard to be followed. Sample preparation (air drying and milling of the sample to particles <1 mm) is included in the displayed price. This analysis is commonly used to evaluate packaging materials' compliance with the PFAS restriction outlined in the new EU Packaging and Packaging Waste Regulation (PPWR). If TF content does not exceed 50 mg/kg (ppm), the material can be considered compliant without further testing.

Phthalates are a group of chemicals widely used as plasticizers, which make plastics more flexible and durable. They have also been used as additives in products such as cosmetics and personal care items. Several phthalates have been identified as endocrine-disrupting agents or as chemicals toxic to reproduction. Exposure to phthalates can occur through: Oral exposure Food: Exposure occurs via migration from food packaging., Children's toys: Children often put toys in their mouths.., Inhalation: Breathing in dust from vinyl flooring or fragrances (like perfumes) can cause exposure to phthalates via inhalation., Skin contact: Phthalates present in cosmetics, lotions, and soaps can be absorbed through the skin.. For other listed matrices apart from cosmetics, the analysis package covers the following substances included in the REACH Authorization List: Substance Abbreviation CAS number Diisobutyl phthalate DIBP 84-69-5 Dibutyl phthalate DBP 84-74-2 Benzyl butyl phthalate BBP 85-68-7 Bis(2-ethylhexyl) phthalate DEHP 117-81-7 Di(n-octyl) phthalate DNOP 117-84-0 Diisononyl phthalate DINP 68515-48-0 Diisodecyl phthalate DIDP 26761-40-0 Products that contain restricted phthalates in concentrations higher than 0.1% may be removed from the market. The analysis package for cosmetic products contains the following phthalates: Substance Abbreviation CAS number Bis(2-ethylhexyl) phthalate DEHP 117-81-7 Benzyl butyl phthalate BBP 85-68-7 Dibutyl phthalate DBP 84-74-2 Diisononyl phthalate DINP 68515-48-0 Di(n-octyl) phthalate DNOP 117-84-0 Diisodecyl phthalate DIDP 26761-40-0 All the above-mentioned substances are prohibited in cosmetic products (Annex II of Regulation (EC) No 1223/2009).

Specific migration of elements listed in Annex II of Commission Regulation (EU) 2020/1245 of 2 September 2020 amending and correcting Regulation (EU) No 10/2011. The test covers the following elements: Lithium (Li), Sodium (Na), Magnesium (Mg), Aluminum (Al), Potassium (K), Calcium (Ca), Chromium (Cr), Manganese (Mn), Iron (Fe), Cobalt (Co), Nickel (Ni), Copper (Cu), Zinc (Zn), Arsenic (As), Cadmium (Cd), Antimony (Sb), Barium (Ba), Lanthanum (La), Europium (Eu), Gadolinium (Gd), Terbium (Tb), Mercury (Hg), Lead (Pb), Sum of lanthanides – Eu, Gd, La, Tb. In addition, the test includes specific migration testing of ammonium ion, which is performed separately from elemental migration analysis.

The substances of very high concern (SVHC) analysis provides comprehensive material screening for SVHC substances as listed in the Registration, Evaluation, and Authorization of Chemical Substances (REACH). The substance list for analysis is updated regularly as new revisions are received from ECHA (twice per year). The maximum allowed concentration of any substance on the SVCH list is 0.1 mass-%. If the product contains more than 0.1% w/w of an SVHC substance, ECHA has to be notified and information on the safe use of the article must be provided to customers upon request. Contact us to request a quote for screening your material for SVHCs. The price of the analysis depends on the sample type.

A biological evaluation plan (BEP) is a critical part of assessing the safety of a medical device. It involves a detailed examination of various aspects such as the device's design & structure, its material composition, manufacturing process & potential contaminants, the intended use, existing test results, and clinical history. The BEP ensures that the device undergoes sufficient biocompatibility testing, with parameters selected from the ISO 10993-1 standard. As a manufacturer, you will need to have a BEP during the regulatory approval process to demonstrate the safety of your medical device. The BEP should be developed during the initial design phase of the medical device. At this stage, manufacturers can identify potential biological risks associated with the device's intended use, materials, and components. A new BEP or updates to the existing one may also be needed if changes are made to the device's design or material composition at a later point. At Measurlabs, we can provide a BEP for a range of medical devices while also guiding manufacturers throughout the process. Do not hesitate to contact us if you are developing a new device, seeking regulatory approval, making changes to an existing product, conducting post-market surveillance, or performing preclinical testing.  We are also happy to create an offer for biocompatibility testing according to the BEP, as well as a biological evaluation report (BER) to summarize the results of the biological evaluation.

Testing for harmful substances in metal jewelry parts according to the requirements of REACH Regulation (EC) No 1907/2006. The test package includes the following tests: Transfer of nickel from jewelry to the human body. Limit value for first-time piercing jewelry 0.2 µg/cm²/week. For other jewelry, the limit is 0.5 µg/cm²/week., Cadmium (concentration test, limit value 0.01% by weight), Lead (concentration test, limit value 0.05% by weight). NOTE: Price is applicable for single jewelry parts (for example earring hooks etc.) and pricing is based on small sample sets. If jewelry includes multiple parts (for example, earrings back part, needle and swinging part), all parts on the sample must be tested, and the price of the analysis is per part. Discount is provided if the number of samples is high. Please ask for an offer from our expert if the tested product includes multiple parts or materials, or if you are planning to deliver a bigger sample set at once.

GC-MS analysis of 16 PAH compounds, which are listed as high-priority pollutants by the U.S. Environmental Protection Agency (EPA). The analyzed PAH compounds are: naphthalene [CAS: 91-20-3], acenaphthylene [CAS: 208-96-8], acenaphthene [CAS: 83-32-9], fluorene [CAS: 86-73-7], phenanthrene [CAS: 85-01-8], anthracene [CAS: 120-12-7], fluoranthene [CAS: 206-44-0], pyrene [CAS: 129-00-0], benz(a)anthracene [CAS: 56-55-3], chrysene [CAS: 218-01-9], benzo(b)fluoranthene [CAS: 205-99-2], benzo(k)fluoranthene [CAS: 207-08-9], benzo (a) pyrene [CAS: 50-32-8], dibenzo(ah)anthracene [CAS: 53-70-3], benzo (ghi) perylene [CAS: 191-24-2], indeno (123cd) pyrene [CAS: 193-39-5].

The burning rate of vertically mounted materials designed for vehicles and buses must be tested with the UN/ECE R118 Annex 8 test before approval for use. Measurlabs offers this and other accredited R118 fire tests. Upon meeting the requirements outlined in Annex 8, the requirements for horizontal flame spread (annex 6) are also met. In the test method, the exposed side of the vertically mounted test specimen is burned from underneath and the burning rate is measured in mm/min.

The melting behavior of fusible materials used in certain motor vehicles must be determined according to Annex 7 of UN/ECE Regulation 118. In the test, it is monitored whether the specimen ignites, creates flaming droplets, and if these droplets ignite cotton wool placed under the specimen. For the material to pass the test, there must be no formation of flaming drops that ignite the cotton wool. Measurlabs can offer accredited test reports for the UN/ECE R118 Annex 7 test, as well as the Annex 6 and Annex 8 tests. Non-isotropic materials must be tested from both sides, which means that double the number of samples is required.

The burning rate of horizontally mounted materials designed to be used in vehicles and buses must be tested with the UN/ECE R118 annex 6 test before they can be approved for use. Measurlabs offers this and the other R118 tests with accreditation. In the test method, the exposed side of the test specimen is burned from underneath and the burning rate is measured and expressed in mm/min.

Analysis of PAH compounds in plastic, rubber, paper, board, and products made from these raw materials (e.g., textiles, toys, packaging materials) as required by the REACH Regulation. Test package includes the following substances: Benzo(a)pyrene [benzo(def)chrysene] [CAS: 50-32-8] , Benzo(e)pyrene [CAS: 192-97-2] , Benzo(a)anthracene [CAS: 56-55-3] , Chrysene [CAS: 218-01-9] , Benzo(b)fluoranthene [CAS: 205-99-2] , Benzo(j)fluoranthene [CAS: 205-82-3] , Benzo(k)fluoranthene [CAS: 207-08-9], Dibenzo(a,h)anthracene [CAS: 53-70-3].

Analysis of fragrance allergens as specified in Commission Regulation (EC) No 1223/2009 on cosmetic products. This wide GC-MS/MS screening covers substances added to Annex III of the cosmetic products regulation by Regulation (EC) No 2023/1545, which added dozens of new entries to the allergen list. Some prohibited substances, such as Lilial and Lyral, are also tested for. The following substances are included in the analysis: Substance Reference number in Regulation 1223/2009 Status Benzyl alcohol 45 Restricted (Annex III) 6-Methyl Coumarin 46 Restricted (Annex III) Amyl cinnamal 67 Restricted (Annex III) Cinnamyl alcohol 69 Restricted (Annex III) Citral, Geranial, Neral 70 Restricted (Annex III) Eugenol 71 Restricted (Annex III) Hydroxycitronellal 72 Restricted (Annex III) Isoeugenol 73 Restricted (Annex III) Amylcinnamyl alcohol 74 Restricted (Annex III) Benzyl salicylate 75 Restricted (Annex III) Cinnamal 76 Restricted (Annex III) Coumarin 77 Restricted (Annex III) Geraniol 78 Restricted (Annex III) Anise alcohol 80 Restricted (Annex III) Benzyl cinnamate 81 Restricted (Annex III) Farnesol 82 Restricted (Annex III) Linalool 84 Restricted (Annex III) Benzyl benzoate 85 Restricted (Annex III) Citronellol 86 Restricted (Annex III) Hexyl cinnamal 87 Restricted (Annex III) Limonene 88 Restricted (Annex III) Methyl 2-Octynoate 89 Restricted (Annex III) alpha-Isomethyl ionone 90 Restricted (Annex III) Evernia prunastri extract 91 Restricted (Annex III) Evernia furfuracea extract 92 Restricted (Annex III) Musk xylene 96 Restricted (Annex III) Musk ketone 97 Restricted (Annex III) Methyl eugenol 102 Restricted (Annex III) Alpha-Terpinene 131 Restricted (Annex III) Terpinolene 133 Restricted (Annex III) Acetyl Hexamethyl indan (Phantolide) 134 Restricted (Annex III) 4-tert.- Butyldihydrocinnamaldehyde (Bourgenoal) 155 Restricted (Annex III) Sum of rose ketones: Alpha-Damascone, cis-Rose ketone 1, trans-Rose ketone 1, Rose ketone 4 (Damascone), Rose ketone 3 (delta-Damascone), trans-Rose ketone 3, cis-Rose ketone 2 (cis-beta-Damascone), trans-Rose ketone 2 (trans-beta-Damascone) 157 Restricted (Annex III) 3-Propylidenephthalide 175 Restricted (Annex III) Acetyl hexamethyl tetralin (Tonalide) 182 Restricted (Annex III) Methyl-N-methylanthranilate 323 Restricted (Annex III) Methyl Salicylate 324 Restricted (Annex III) Acetyl Cedrene 327 Restricted (Annex III) Amyl Salicylate 328 Restricted (Annex III) Anethole (analyzed as trans-Anethole) 329 Restricted (Annex III) Benzaldehyde 330 Restricted (Annex III) Camphor 331 Restricted (Annex III) Beta-Caryo-phyllene 332 Restricted (Annex III) Carvone 333 Restricted (Annex III) Dimethyl Phenethyl Acetate (analyzed as Dimethylbenzyl Carbinyl Acetate) 334 Restricted (Annex III) Hexadecanolactone 335 Restricted (Annex III) Hexamethylindanopyran 336 Restricted (Annex III) Linalyl Acetate 337 Restricted (Annex III) Menthol 338 Restricted (Annex III) Trimethylcyclopentenyl Methylisopentenol 339 Restricted (Annex III) Salicylaldehyde 340 Restricted (Annex III) Santalol (analyzed as alpha-Santalol, beta-Santalol, Santalol (sum of isomers)) 341 Restricted (Annex III) Sclareol 342 Restricted (Annex III) Terpineol (analyzed as alpha-Terpineol, beta-Terpineol, gamma-Terpineol, Terpineol (sum of isomers)) 343 Restricted (Annex III) Tetramethyl acetyloctahydronaphthalenes 344 Restricted (Annex III) Trimethylbenzenepropanol 345 Restricted (Annex III) Vanillin 346 Restricted (Annex III) Versalide 362 Restricted (Annex III) Eugenyl Acetate 368 Restricted (Annex III) Geranyl Acetate 369 Restricted (Annex III) Isoeugenyl Acetate 370 Restricted (Annex III) Pinene (analyzed as alpha-Pinene, beta-Pinene, Pinene (sum of isomers)) 371 Restricted (Annex III) Musk Ambrette 414 Prohibited (Annex II) Moskene 421 Prohibited (Annex II) Musk Tibetene 422 Prohibited (Annex II) 4-(4-Hydroxy-4-methylpentyl) cyclohex-3-ene1-carbaldehyde (Lyral) 1380 Prohibited (Annex II) 2,6-Dihydroxy-4-methyl-benzaldehyde (atranol) 1381 Prohibited (Annex II) 3-Chloro-2,6-Dihydroxy-4-methyl-benzaldehyde (chloroatranol) 1382 Prohibited (Annex II) 2-(4-tert-butylbenzyl) propionaldehyde (Lilial) 1666 Prohibited (Annex II) Traseolide (musk fragrance) - Not listed Cashmeran (musk fragrance) - Not listed Celestolid (musk fragrance) - Not listed In most cases, the presence of individual fragrance allergens must be indicated on cosmetics packaging if their concentration exceeds 0.001% in leave-on products or 0.01% in rinse-off products. More detailed restrictions are outlined in annexes to the consolidated version of Regulation (EC) 1223/2009.

Analysis package for mycotoxins listed in Commission Regulation (EU) No 2023/915, including the following determinations: Aflatoxin B1, B2, G1, G2, Ochratoxin A, T-2, HT-2 toxins, Deoxynivalenol, Zearalenone. Testing of the listed mycotoxins is usually required for almost all types of cereals and cereal products, including foods for infants and young children. We can also offer additional mycotoxin analyses, including for ergot alkaloids, patulin, and alternaria toxins. Do not hesitate to ask for more information or request a quote.

The following analyses are included in this nanoparticle analysis package, intended to characterize nanoforms according to the REACH Regulation. Particle size distribution and aspect ratios by SEM-EDX Preparation with isopropanol, Sample dispersion on a slide, with centrifugation, SEM analysis and particle count by image analysis, Nanoparticle detection and classification according to the 2022 EC recommendation on the definition of nanomaterial, Reporting of PSD parameters for ~300 particles, including the following: PSD diagram, accumulated and individual., Feret min (min, d10, d25, d50, d75, d90, d95, max), Feret max (min, d10, d25, d50, d75, d90, d95, max), Equivalent circular diameter (min, d10, d25, d50, d75, d90, d95, max), Aspect ratio (calculated based on individual Feret min and Feret max measurements), Number based nano-fraction (%).. Crystal phase analysis by XRD/Rietveld method Sample preparation: drying, grinding, X-ray preparation, XRD analysis over an angular range extending from 10° to 90°, Identification of the crystalline phases present in the sample, Semi-quantitative analysis of phase distribution, using the Rietveld method, Interpretation of diffractograms. Chemical composition/purity by ICP-AES and CHNS analysis ICP-AES quantification of inorganic and metallic elements: Ag, Al, As, B, Ba, Be, Bi, Ca, Cd, Co, Cr, Cu, Fe, K, Li, Mg, Mn, Mo, Na, Ni, P, Pb, S, Se, Sb, Si, Sn, Sr, V, Zn, Ti, and Tl, Determination of C, H, N, and S with an elemental analyzer. Volume-specific surface area (VSSA) and VSSA diameter calculations (optional) BET specific surface area measurement of powder by nitrogen adsorption, True (skeletal) density measurement by He pycnometry, excluding intergranular and intragranular porosity, Both analyses include sample preparation. You can request a quote for the analysis using the form below. Please note that the OECD 125 guideline does not apply to this analysis.

A biological evaluation report (BER) or biological risk assessment report (BRA) collects and evaluates the results of biological evaluation studies and concludes the medical device's biological risk. It is a comprehensive analysis considering chemical and biological test results as well as toxicological evaluation of the extractables that could be released from the device during its usage. The biological evaluation report is needed as a part of the regulatory approval and often requires strong expertise in the biological risk evaluation of medical devices, taking into account the requirements of ISO 10993- standard family and local regulations (FDA, MDR). The biological evaluation plan (BEP) and sufficient testing need to be completed before the BER can be prepared. Measurlabs can support medical device manufacturers with BER preparation. We can also provide the required testing and a BEP if these have not yet been completed.

Determination of selected volatile organic compounds (VOC) in water using the GC-MS and GC-FID techniques. Analysis can be conducted according to the following standard methods: EPA 624, EPA 5021A, EPA 8260, EPA 8015, EN ISO 10301, ISO 11423-1, and EN ISO 15680 The results of the analysis are reported in µg/L. Analysis includes the following analytes: Analyte: Reporting limits: chloromethane 1 µg/l bromomethane 1 µg/l dichloromethane 0.1 µg/l dibromimetaani 1 µg/l bromochloromethane 2 µg/l trichloromethane (chloroform) 0.1 µg/l tribromomethane (bromoform) 0.2 µg/l bromodichloromethane 0.1 µg/l dibromochloromethane 0.1 µg/l sum 4 trihalometanit 0.5 µg/l tetrachloromethane 0.1 µg/l trichlorofluoromethane 1 µg/l dichlorodifluoromethane 1 µg/l monochloroethane 1 µg/l 1,1-dichloroethane 0.1 µg/l 1,2-dichloroethane 0.1 µg/l 1,2-dibromietaani 0.5 µg/l 1,1,1-trichloroethane 0.1 µg/l 1,1,2-trichloroethane 0.1 µg/l 1,1,1,2-tetrachloroethane 0.1 µg/l 1,1,2,2-tetrachloroethane 1 µg/l vinyl chloride 0.1 µg/l 1,1-dichloroethene 0.1 µg/l cis-1,2-dichloroethene 0.1 µg/l trans-1,2-dichloroethene 0.1 µg/l amount of 1,2-dichloroethene 0.2 µg/l trichloroethylene 0.1 µg/l sum of 11 chlorinated hydrocarbons 1.1 µg/l tetrachloroethene 0.1 µg/l Sum of trichloroethylene and tetrachloroethylene 0.2 µg/l sum 5 chlorinated ethylenes 0.5 µg/l 1,2-dichloropropane 1 µg/l 1,3-dichloropropane 1 µg/l 2,2-dichloropropane 1 µg/l 1,2,3-trichloropropane 1 µg/l 1,2-dibromo-3-chloropropane 1 µg/l 1,1-dichloro-1-propene 1 µg/l cis-1,3-dichloro-1-propene 1 µg/l trans-1,3-dichloropropene 1 µg/l hexachlorobutadiene 1 µg/l 2-chlorotoluene 1 µg/l 4-chlorotoluene 1 µg/l monochlorobenzene 0.1 µg/l bromobenzene 1 µg/l 1,2-dichlorobenzene 0.1 µg/l 1,3-dichlorobenzene 0.1 µg/l 1,4-dichlorobenzene 0.1 µg/l amount of 3 dichlorobenzene 0.3 µg/l 1,2,3-trichlorobenzene 0.1 µg/l 1,2,4- trichlorobenzene 0.1 µg/l 1,3,5-trichlorobenzene 0.1 µg/l amount of 3 trichlorobenzene 0.4 µg/l benzene 0.1 µg/l toluene 0.5 µg/l ethylbenzene 0.1 µg/l o-xylene 0.1 µg/l m/p-xylene 0.2 µg/l sum of xylenes 0.3 µg/l sum of BTEX 1 µg/l styrene 0.2 µg/l isopropylbenzene 1 µg/l n-propylbenzene 1 µg/l 1,2,4-trimethylbenzene 1 µg/l 1,3,5-trimethylbenzene 1 µg/l n-butylbenzene 1 µg/l sec-butylbenzene 1 µg/l tert-butylbenzene 1 µg/l p-isopropyltoluene 1 µg/l naphthalene 1 µg/l Diisopropyl ether (DIPE) 0.6 µg/l ETBE (ethyl tert-butyl ether) 0.2 µg/l MTBE (methyl tert-butyl ether) 0.2 µg/l tert-amyl ethyl ether (TAEE) 0.2 µg/l TAME 0.2 µg/l tert-butyl alcohol (TBA) 5 µg/l ethanol 100 µg/l A customized offer can also be prepared if you are interested in analyzing only individual compounds from a sample. Suitable sample containers for analysis can be ordered through us. Sample containers picked up from Measurlabs are included in the price of the analysis, but sample containers can also be shipped to the customer for a separate fee.

The purpose of cleaning validation studies is to show that reusable medical devices can be reprocessed effectively between uses so that patients are not exposed to pathogens. Depending on the device’s intended use and classification, appropriate reprocessing steps may include cleaning, disinfection, and/or sterilization. For cleaning validation more specifically, the testing procedure consists of three steps: Simulated contamination with artificial soils that accurately reflect clinically relevant soils, such as blood and other bodily fluids. , Cleaning (manual and/or automated), carefully following the manufacturer's instructions for parameters such as detergents, cleaning tools, water quality, and temperature. , Inspection, both visually and using quantitative methods relevant to the test soil (e.g., proteins, total organic carbon, or hemoglobin), to assess whether residual contaminants remain on the device.. Successful cleaning validation is often sufficient for non-critical reusable devices, such as blood pressure cuffs, monitors, and clutches. Semi-critical and critical devices will require further disinfection and/or sterilization validation studies, which we can also offer. The displayed example price covers a manual cleaning validation study with 6 reprocessing cycles and cleanability evaluations with visual inspection & protein content measurement. Test protocol formulation and reporting are also included.

Determination of industrial compostability of plastic-based products and packaging according to ASTM D6400. The standard defines pass/fail criteria for labeling products as compostable in municipal or industrial aerobic composting facilities, covering both the material itself and the compost it produces. Four complementary tests are required for a full compostability assessment: Aerobic biodegradation: samples are incubated under composting conditions and CO₂ evolution is monitored; the pass criterion is ≥90% carbon conversion to CO₂ within the defined timeframe., Disintegration: composted material is sieved through a 2 mm mesh; the pass criterion is ≤10% fragment mass remaining., Ecotoxicity: compost produced from the test material is applied to plant tests measuring germination rate and biomass relative to blank controls; both must reach ≥90% of control values., Heavy metals: concentrations of regulated metals in the material or residue must not exceed 50% of the limits prescribed for composts and biosolids under EPA regulations.. Results are reported as percentage carbon mineralization, percentage mass passing the sieve, plant germination rate and relative biomass as a percentage of controls, and metal concentrations in mg/kg dry weight. ASTM D6400 is the primary standard for substantiating industrial compostability claims in the U.S. In Europe, the functionally comparable standard is EN 13432, which is referenced in the EU Packaging and Packaging Waste Regulation (PPWR).

Determination of aerobic biodegradability in seawater according to OECD 306, applicable to chemicals and organic materials dissolved or dispersed in collected seawater. Two test formats are available: shake flask and closed bottle. Seawater is sampled from the field and characterized for temperature, salinity, and optionally DOC and other parameters before use; it may be filtered, settled, or aged prior to incubation. Incubations are carried out in closed glass containers under aerobic conditions at approximately 15–20°C in the dark or under diffuse light for up to 60 days. The shake-flask format tracks ultimate degradation by repeated DOC measurements over time, quantified by persulfate/UV, persulfate with elevated temperature, or high-temperature combustion. , The closed-bottle format monitors dissolved oxygen consumption at defined intervals (e.g. days 0, 5, 15, and 28). Ancillary options include heterotrophic plate counts, ATP or other microbial-activity assays, and specific chemical analysis of the test substance.. Results are presented as time-course degradation curves. Shake-flask outputs report DOC-based curves with lag phase, slope, and t50, with percentage degradation typically reported at 60 days. Closed-bottle outputs report oxygen-uptake curves with lag phase and t50, with percentage degradation reported at 28 days or test conclusion. Data are compiled on standardized sheets with validity checks. The method is referenced in several regulatory persistence and biodegradability assessment frameworks. Under REACH, OECD 306 is recognised by ECHA as a ready biodegradability test method alongside OECD 301 and 310, and data generated under the guideline can be submitted in REACH registration dossiers to fulfil information requirements on environmental fate and behaviour. OECD 306 is also listed as an accepted ready-biodegradability method under the REACH microplastics restriction (Commission Regulation (EU) 2023/2055, Appendix 15). Additionally, the EU Ecolabel for lubricants lists OECD 306 as a recommended biodegradability test method.

With this label check, the information provided on a food label is reviewed against the requirements of Regulation (EU) No 1169/2011 on food information to consumers. Applicable implementing regulations are also considered (e.g., (EU) No 2018/775 on indicating the primary ingredient's country of origin). According to EU regulations, mandatory food information for almost all prepackaged foods includes the following: The name of the food, The list of ingredients, Any ingredient or processing aid that may cause allergies or intolerances, Quantity of certain ingredients or categories of ingredients, Net quantity of the food, The date of minimum durability ('best before' or 'use by' date), Any special storage conditions and/or conditions of use, The name or business name and address of the food business operator, The country of origin or place of provenance, Instructions for use where it would be difficult to make appropriate use of the food in the absence of such instructions, The actual alcoholic strength by volume for beverages containing more than 1.2 % by volume of alcohol, Nutrition declaration. The label check can be combined with laboratory analyses covering parameters related to EU or national legislation. If this is the case, the analysis results are reviewed as part of the check. Nutritional and vitamin content analysis results are evaluated based on this Commission guidance document. Other parameters that can be assessed in the review process include, for example, the following: Contaminants and undesirable substances, as listed in Regulation (EU) No 2023/915, Pesticide residues as in Regulation (EU) No 396/2005, Food additives as in Regulation (EC) No 1333/2008, Food flavourings as in Regulation (EC) No 1334/2008, Acrylamide as in Regulation (EU) No 2017/2158. Photographic evidence of the product label, including all the required details, is provided with the test report. Contact us for more information about the food label check and a quote for related testing services.

Assessment of the inhibitory effects of chemicals on activated sludge microorganisms by measuring oxygen uptake according to OECD Test Guideline 209 (equivalent to EU Method C.11 under Commission Regulation (EC) No. 440/2008). The test is applicable to water-soluble, poorly soluble, and volatile substances, with appropriate measures taken to maintain exposure concentrations for volatile compounds. Activated sludge from a wastewater treatment plant receiving predominantly domestic sewage is exposed to a geometric series of test substance concentrations together with synthetic sewage feed and dilution water for 3 hours at 20 ± 2°C and pH 7.5 ± 0.2. Oxygen uptake is measured using a dissolved oxygen electrode in a closed measurement cell. Where required, total respiration can be partitioned into: Heterotrophic respiration (carbon oxidation), Nitrification (ammonium oxidation), determined by measuring oxygen uptake with and without N-allylthiourea, a specific nitrification inhibitor. An optional shorter contact time (e.g., 30 minutes) is available for rapidly degrading or volatile compounds. Quality controls include blanks, optional abiotic controls (no inoculum), and a reference substance (typically 3,5-dichlorophenol) to confirm sludge sensitivity. Results are reported as oxygen uptake rates and percentage inhibition relative to controls. Primary endpoints are ECx values (e.g., EC50) and/or NOEC, expressed in mg/L. Results also identify non-inhibitory concentrations suitable for use in subsequent biodegradability testing. The method is accepted in REACH registration dossiers submitted to ECHA, where it fulfills the information requirement for toxicity to microorganisms. The closely related U.S. EPA guideline OPPTS 850.6800 (Modified Activated Sludge, Respiration Inhibition Test for Sparingly Soluble Chemicals) covers a modified version of the same test for poorly soluble substances.

Determination of ready biodegradability in aerobic aqueous conditions in accordance with OECD 301 guideline, applicable to polymers, chemicals, and other organic materials.  The test item is incubated in mineral medium with a microbial inoculum for 28 days under controlled aerobic conditions, alongside blanks, reference substance controls, and, where relevant, toxicity controls. Results are reported as the percentage of biodegradation, along with a degradation curve. A pass/fail interpretation against the criteria specified in the guideline will also be provided. Measurlabs offers testing with three of the six methods outlined in OECD 301: OECD 301B – CO₂ evolution test (result expressed against theoretical CO₂ production), OECD 301D – oxygen depletion in the closed bottle (result expressed against theoretical oxygen demand), OECD 301F – oxygen uptake by manometric respirometry (result expressed against theoretical oxygen demand). Method selection depends on sample properties such as solubility, volatility, and expected biodegradation behavior.  All three tests can be used to support compliance with the REACH microplastics restriction under Commission Regulation (EU) 2023/2055, which lists OECD 301B, D, and F among accepted methods for demonstrating degradability. Biodegradable polymers are exempted from the restriction.

This screening method (OECD 310, CO₂ in sealed vessels/headspace test) determines ready biodegradability by measuring aerobic CO₂ mineralisation and expressing the extent of biodegradation as a percentage of the theoretical maximum inorganic carbon (ThIC). It is applicable to a wide range of chemical substances, including water‑soluble and water‑insoluble materials, poorly soluble compounds, and strongly adsorbing substances. It can also be adapted to volatile compounds through appropriate headspace-to-liquid ratios and handling. The test can be used to assess the ultimate biodegradability of surfactants in detergents under Regulation (EC) No 648/2004. EN ISO 14593:1999 (the CO₂ headspace test) is referenced in the regulation, and OECD 310 is the technically equivalent OECD guideline. Surfactants are considered readily biodegradable if they achieve ≥60% mineralisation within 28 days. The same pass criterion also applies under the REACH microplastics restriction (Commission Regulation (EU) 2023/2055), which explicitly lists OECD 310 as an accepted biodegradability test method. In the test, samples are incubated in sealed bottles with an air headspace to supply oxygen for aerobic degradation, and CO₂ evolved during incubation is quantified as inorganic carbon (IC) against blank controls at scheduled sampling times. Two principal measurement approaches are described: headspace gas can be acidified to pH <3 and analyzed for IC, with results recorded as mg C/L, or the liquid phase can be treated with NaOH to absorb CO₂ and then injected to the IC analyzer. For water‑soluble substances, an optional supporting endpoint measures primary biodegradation via DOC removal, determined on filtered liquid using a DOC analyzer.  Reported outputs are the percent biodegradation expressed as % of ThIC (calculated from IC recovered in liquid plus headspace versus blanks), the intermediate IC concentrations from the analyzer in mg C/L, and, where performed, DOC removal values from the DOC analyzer.

This analysis package is intended to determine whether food packaging and beverage bottles can be considered reusable in the framework of the Single-Use Plastic (SUP) Directive (EU) 2019/904. The following tests are included: Overall migration testing for repeated use with 10% ethanol, 3% acetic acid, and olive oil (simulants A, B, and D2), Dishwasher resistance testing according to EN 12875-1 with 25 wash cycles. The EU Commission’s interpretations of the SUP legislation state that reusability can be evaluated using the test method EN 12875-1 (Mechanical dishwashing resistance of utensils). If plastic articles can be washed 25 times in a dishwasher, they can be considered reusable, as they maintain their usability and properties throughout multiple uses. The test package also includes overall migration testing for repeated use to ensure that the article remains inert when used multiple times. By default, testing is done to establish compliance with all types of foods (i.e., moist and dry, acidic and non-acidic, and fatty foods). Note: The price applies to articles that have already been cleared for food contact as single-use articles. If a full set of tests for compliance according to Regulation (EU) No 10/2011 is needed, our experts are happy to provide a quote.

Measurement of the solution/extraction behavior of polymers in water according to the OECD 120 test guideline. The test is typically applied to polymer powders or granules, preferably with particle size in the approximate range of 0.125-0.25 mm, to determine how much polymer-related material passes into the aqueous phase under defined conditions. In the test, three 10 g test portions are agitated with 1 L of water at 20 °C for 24 hours in stoppered vessels. The aqueous phase is separated by centrifugation or filtration and analyzed to determine solubility. Results are reported as the concentration of polymer-related material in the aqueous phase, determined by direct analysis, residue analysis after evaporation, or gravimetric determination of the undissolved fraction. This test can be used to prove polymer solubility for compliance with the REACH microplastic restriction outlined in Commission Regulation (EU) 2023/2055. The pass criterion is solubility higher than 2g/liter.