Osmolality measurement

UPLC-MS/MS analysis for determining the melatonin content in dietary supplements. According to Regulation (EU) No 432/2012, melatonin supplements may be marketed with the following health claims: "Melatonin contributes to the alleviation of subjective feelings of jet lag." The claim can be used if the product contains at least 0.5 mg of melatonin per portion., "Melatonin contributes to the reduction of time taken to fall asleep." The claim can be used if the product contains at least 1 mg of melatonin per portion..

Determination of total sugar content, expressed as glucose, of food and feed with the Luff–Schroorl titration method.

Determination of reducing sugar content, expressed as glucose, from food and feed with the Luff–Schoorl titration method.

Hot-stage microscopy (HSM) analysis enables the direct visualization of materials under controlled temperature conditions. Capabilities include: Examining compound morphology and particle characteristics., Observing solid-solid transformations, melting/liquefaction, solidification, sublimation, and evaporation., Monitoring how different compounds interact, dissolve, or react with each other., Tracking crystal growth and growth rates., Utilizing the Kofler mixed fusion method for salt/co-crystal screening., Observing oxidation and other chemical reactions as they occur under heat.. The results will include microscope pictures and video showing the transitions during heating. Measurement specifications: Temperature range: 25 °C to 375 °C, Humidity control: 5–90% RH. Instrument details: The instrument set-up comprises a heating stage (hot stage) with a sample holder, coupled with a polarized-light microscope and a system that allows temperature measurements and video/picture recording.

Determination of osmolarity of liquid samples using a freezing point osmometer according to the European Pharmacopoeia method Ph. Eur 2.2.35. Osmolarity is defined as the number of osmols per liter of liquid, reflecting the total number of dissolved ionic and molecular substances present in the solution in molarity. The results of the analysis are reported in mOsm/L. NOTE: The total concentration of the solute in the product needs to be provided (expressed in g/mL), as this information is necessary for the calculation of osmolarity. Without this information, only the product's osmolality (mOsm/kg) can be determined. If the product is a powder, please provide instructions for the preparation of the solution. Analysis can also be performed under GMP - please ask us for an offer.

Determination of starch in food with a spectrophotometric method.

This analysis package is used to determine the amount of polycyclic aromatic hydrocarbons in food, feed, and dietary supplements. The package covers the following substances, known together as PAH 4: benzo(a)pyrene, benz(a)anthracene, benzo(b)fluoranthene, chrysene. According to EU regulations, materials that potentially require PAH testing include: foods and dietary items intended for infants or young children, oils and fats, smoked meat and fish, smoked products prepared using traditional methods, smoke flavorings. Compliance can be evaluated against the maximum levels set in Regulation (EU) 2023/915 on food contaminants and Regulation (EC) No 2065/2003 on smoke flavorings.

Determination of microplastics present in food samples using Raman or FTIR microspectroscopy. The analysis report will specify different types of polymers by size (1-50 µm, 50–100 µm, 100–500 µm, >500 µm).

Determination of vitamin B7 (biotin) in food with an HPLC-UV-VIS method, or in supplements with a UPLC-MS/MS method. According to Regulation (EU) No 1169/2011, the biotin content of food products may be included in the nutrition declaration if it is present in significant amounts. The daily reference intake for biotin is 50 µg, and biotin content can be declared if the product contains at least: 7.5 µg/100 g or 100 ml in products other than beverages (15% of reference intake), 3.75 µg/100 ml in beverages (7.5% of reference intake), 7.5 µg per portion if the package contains a single portion (15% of reference intake). Foods that contain at least the above amounts of biotin can be labeled with the nutrition claim "Source of biotin." Additional nutrition and health claims related to vitamin B7 can be applied in accordance with Regulations (EC) No 1924/2006 and (EU) No 432/2012.

Determination of patulin content in food, feed, and dietary supplements with an HPLC method based on EN 14177. Patulin is a mycotoxin produced by several different species of fungi. Apples and apple products are especially susceptible to patulin contamination, but the toxin can also be found in other foods. Regulation (EU) 2023/915 sets maximum levels for patulin in various high-risk products, such as juices, apple products, and baby food. The EU has also addressed the means to reduce and prevent patulin contamination in apple juices and apple juice-based beverage ingredients in a Commission Recommendation from 11 August 2003.