Testing services / Specific migration testing – primary aromatic amines (PAA), extended package

Specific migration testing – primary aromatic amines (PAA), extended package

Name: Specific migration testing – primary aromatic amines (PAA), extended package
Brand: Measurlabs
SKU: a41b7c0b-3c56-42a4-8121-a34c3f6c8b39
Price: 379 EUR
Availability: InStock

Primary aromatic amines (PAA) are a class of compounds that are generated when residual isocyanate groups in food contact materials react with the water in foods. In addition, articles in which aniline, benzidine, or other PAAs have been used as precursors for pigments or as curing agents can be a source for restricted PAA.

Certain PAAs are known carcinogens, and these are listed in entry 43 to Appendix 8 of Annex XVII to Regulation (EC) No 1907/2006 of the European Parliament and Council (known as the REACH Regulation). These PAAs are not allowed to migrate into food or food simulants.

Primary aromatic amine testing is especially relevant for products that contain, for example, the following:

Aromatic isocyanate groups containing SML substances
Polyurethane-based materials
Azo dyes
Recycled plastic

This test package includes the analysis of the following substances:

Substance	CAS number
2-Amino-4-nitrotoluene	99-55-8
2-Naphthylamine	91-59-8
2,4-Diaminoanisole	615-05-4
2,4-Toluenediamine	95-80-7
2,4,5-Trimethylaniline	137-17-7
3,3'-Dichlorobenzidine	91-94-1
3,3'-Dimethoxybenzidine	119-90-4
4,4ʹ-Diamino-3,3ʹ-dimethyldiphenylmethane,	838-88-0
3,3'-Dimethylbenzidine	119-93-7
4-Aminoazobenzene	60-09-3
4-Aminodiphenyl	92-67-1
4-Chloro-o-toluidine	95-69-2
4,4'-Diaminodiphenylmethane	101-77-9
4,4ʹ-Methylene-bis(2-chloroaniline)	101-14-4
4,4'-Oxydianiline	101-80-4
4,4'-Thiodianiline	139-65-1
Benzidine	92-87-5
o-Aminoazotoluene	97-56-3
o-Anisidine	90-04-0
o-Toluidine	95-53-4
p-Chloroaniline	106-47-8
p-Cresidine	120-71-8
1,2-Phenylenediamine	95-54-5
1,3-Phenylenediamine	108-45-2
1,4-Phenylenediamine	106-50-3
1,5-Diaminonaphthalene	2243-62-1
2-Aminobenzamide	88-68-6
2,4-Dimethylaniline	95-68-1
2,4'-Methylenedianiline	1208-52-2
2,5-Dimethoxy-4-chloroaniline	6358-64-1
2,6-Diaminotoluene	823-40-5
2,6-Dimethylaniline	87-62-7
3-Chloroaniline	108-42-9
4-Aminobenzamide	2835-68-9
4-Methylaminosulfonyl-p-cresidine	49564-57-0
4,4′-Diaminodiphenyl sulfone	80-08-0
5-Amino-6-methyl-2-benzimidazolone	67014-36-2
Aniline	62-53-3
4-Aminotoluene-3-sulfonic acid	88-44-8
N,N-Dimethylaniline	121-69-7
p-Toluidine	106-49-0
Sum of primary aromatic amines	-

More information about the method:

LC-MS analysis (LC-MS)

Suitable sample matrices: Plastic, rubber
Required sample quantity: Film: 2xA4-size sheets. Article (< 250 ml): 6 items. Article (> 250 ml): 3 items. Other: 3 dm2
Typical turnaround time: 4 weeks after receiving the samples
Detection limit: 0.0005 mg/kg
Available quality systems: Accredited test method
Device types: LC-MS
Standard: EN 13130-1
Method expert: Niko Markkinen