Specific migration testing – non-intentionally added substances (NIAS), LC-QTOF-MS

Analysis of non-intentionally added substances (NIAS), which are chemicals that are present in a food contact material (FCM) or food contact article (FCA) but have not been added for a technical reason during the production process.

NIAS chemicals have various sources and can be grouped into side products, breakdown products, and contaminants.

Analysis is available for various simulants apart from the dry food simulant (Tenax) and olive oil. The price includes a simple risk assessment based on EU regulations for food contact materials, and EFSA's Threshold of Toxicological Concern (TTC) approach. More extensive risk assessment is available upon request.

The analysis is performed using the LC-QTOF-MS method (liquid chromatography quadrupole time-of-flight mass spectrometry).

Suitable sample matrices
Plastic, food contact materials with polymeric coatings, paper and board
Required sample quantity
Film: 2xA4-size sheets. Article (< 250 ml): 6 items. Article (> 250 ml): 3 items. Other: 3 dm2
Typical turnaround time
6 weeks after receiving the samples
Detection limit
LOQ 0.01 mg/kg (semi-quantitative)
Available quality systems
Accredited testing laboratory
Device types


Price per sample (Excl. VAT):
546 €

We also charge a 97 € service fee per order.

Large batches of samples are eligible for discounts.

Questions? We're happy to help.

Questions? We're happy to help.

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Have questions or need help? Email us at or call +358 50 336 6128.