Specific migration testing – non-intentionally added substances (NIAS), LC-QTOF-MS
Analysis of non-intentionally added substances (NIAS), which are chemicals that are present in a food contact material (FCM) or food contact article (FCA) but have not been added for a technical reason during the production process.
NIAS chemicals have various sources and can be grouped into side products, breakdown products, and contaminants.
Analysis is available for various simulants apart from the dry food simulant (Tenax) and olive oil. The price includes a simple risk assessment based on EU regulations for food contact materials, and EFSA's Threshold of Toxicological Concern (TTC) approach. More extensive risk assessment is available upon request.
The analysis is performed using the LC-QTOF-MS method (liquid chromatography quadrupole time-of-flight mass spectrometry).
- Suitable sample matrices
- Plastic, food contact materials with polymeric coatings, paper and board
- Minimum sample amount
- Film: 2xA4-size sheets. Article (< 250 ml): 6 items. Article (> 250 ml): 3 items. Other: 3 dm2
- Typical turnaround time
- 6 weeks after receiving the samples
- Detection limit
- LOQ 0.01 mg/kg (semi-quantitative)
- Quality system
- Accredited testing laboratory
- Device types