Specific migration testing – PHBH oligomers

Analysis to determine the specific migration of fluorescent whitening agent 2,5-bis(5-tert-butyl-2-benzoxazolyl)thiophene, known by the trade name Uvitex OB [CAS: 7128-64-5], from a sample or material intended for food contact. The substance is listed under FCM 500 and Ref No. 38560 in European Commission Regulation No 2011/10 on plastic food contact materials. The specific migration limit (SML) for Uvitex OB is 0.6 mg/kg of food.

Specific migration testing to measure the transfer of 1,6-hexamethylene-bis[3-(3,5-di- tert-butyl-4-hydroxyphenyl) propionamide] into food. The substance is better known by the trade name Irganox 1098 [CAS: 23128-74-7]. Irganox 1098 is listed as FCM 631 with Ref No. 59120 in Regulation (EU) No 10/2011 on plastic food contact materials. The specific migration limit (SML) for the substance is 45 mg/kg of food.

Accredited laboratory analysis for determining the specific migration of 1,3-butadiene [CAS: 106-99-0] from plastic and rubber-based materials intended for food contact. The compound is listed in Regulation (EU) No 10/2011 on plastic food contact materials with FCM substance number 223 and Reference number 13630. The specific migration limit (SML) for butadiene is ND, which means that there must not be detectable migration into food with a detection limit of 0.01 mg/kg. In addition, the concentration of butadiene in the final product must not exceed 1 mg/kg. According to German BfR Recommendation XXI, the above restrictions also apply to materials based on natural and synthetic rubber, such as nitrile gloves.

Test package for beeswax-coated wraps to evaluate suitability for food contact according to Regulation (EC) 1935/2004 (Article 3). The package is based on German BfR document "Beeswax cloths: what should you look out for?" The details of the analyses included are presented in the table below: Test parameter Test method Note Transfer of odor and flavor into food DIN 10955 Test performed with a model food Pesticide screening LC-MS, GC-MS Includes analysis of 715 substances Migration of mineral oil (MOSH/POSH & MOAH) hydrocarbons Online LC-GC-FID Simulant and conditions decided based on the intended use of the product Migration of primary aromatic amines LC-MS/MS Simulant and conditions decided based on the intended use of the product More information can be found in this FAQ document by BfR.

Determination of the specific migration of 9,9-bis(methoxymethyl)fluorene [CAS: 182121-12-6 ] from a plastic material intended for food contact. The substance is listed under FCM No. 779 and Ref No. 39815 in European Commission Regulation No 10/2011. The specific migration limit (SML) is 0.05 mg/kg of food. 9,​9-​bis(methoxymethyl)​​fluorene is used in the preparation of polypropylene by heterogeneous Ziegler-Natta catalysts.

Test package for single-use nitrile gloves to assess food contact compliance (for all foodstuffs) according to Germany's BfR XX1/1 "Commodities based on natural and synthetic rubber in contact with food" (as of 01.09.2024) and Regulation (EC) No 1935/2004. The test package covers selected general requirements for nitrile rubber. Analysis to determine the specific migration of nitrile rubber monomers (i.e., acrylonitrile and 1,3-butadiene) is also included. The substances have specific migration reference (SMR) values defined in Table 1 of BfR XXI. The table below lists the covered parameters, test methods, and compliance requirements: Test parameter Simulant(s) Test method Requirement Overall migration 10% ethanol, 3% acetic acid, olive oil EN 1186-1, -2, -3 ≤ 10 mg/dm2 Sensory analysis Water DIN 10955 No transfer of taste or odor Total transfer of zinc 3% acetic acid In-house ICP-MS ≤ 25 mg/kg of food Total transfer of aluminum 3% acetic acid In-house ICP-MS ≤ 1 mg/kg of food Total transfer of lead 3% acetic acid In-house ICP-MS ≤ 0.01 mg/kg of food Extractable primary aromatic amines 3% acetic acid In-house LC-MS/MS ≤ 0.002 mg/l of extract (per substance) Total transfer of formaldehyde 3% acetic acid In-house method ≤ 6 mg/kg of food Specific migration of butadiene olive oil In-house GC-MS/FID ≤ 0.01 mg/kg of food Specific migration of acrylonitrile 10% ethanol, 3% acetic acid, olive oil In-house GC-MS/FID ≤ 0.01 mg/kg of food The following parameters are not included in the package, but they can be analyzed separately upon request: Colorfastness, Release of N-nitrosamines and nitrosatable substances, Release of secondary aliphatic amines, Transfer of antimicrobial components (EN 1104).

Specific migration of vinyl acetate [CAS: 108-05-4] from a sample or material intended for food contact. Vinyl acetate is listed with FCM 231 and Ref No. 10120 in European Commission Regulation No 10/2011 with an SML value of 12 mg/kg of food.

Specific migration of mineral oil hydrocarbons (MOH), including mineral oil saturated hydrocarbons (MOSH) with polyolefin oligomeric hydrocarbons (POSH) and mineral oil aromatic hydrocarbons (MOAH) from food contact materials (FCM) into a food simulant. Analysis is possible with food simulants 10%, 20%, 50%, and 95% ethanol, 3% acetic acid, iso-octane, olive oil, and Tenax. The price includes testing with one simulant. The results are reported as the concentrations of fractions of MOSH/POSH and MOAH, with grouping based on the number of carbon atoms in the substances. The reported fractions are listed in the table below: MOSH/POSH (C10-C50), total MOAH (C10-C50), total MOSH/POSH (≥C10-≤C16) MOAH (≥C10-≤C16) MOSH/POSH (>C16-≤C20) MOAH (>C16-≤C25) MOSH/POSH (>C20-≤C25) MOAH (>C25-≤C35) MOSH/POSH (>C25-≤C35) MOAH (>C35-≤C50) MOSH/POSH (>C35-≤C40) MOSH/POSH (>C40-≤C50) POSH are not part of MOH but can be present in polyolefin plastics, such as polyethylene (PE) and polypropylene (PP). MOSH and POSH have very similar structures and they tend to elute together in chromatography. Thus in polyolefin plastics and materials with polyolefin layers, it is usually impossible to separate MOSH and POSH with normal analysis techniques. The analysis includes a compliance assessment according to the following references: MOSH fraction: in-house risk assessment POSH fraction: Plastics Europe documentation Polyolefin oligomers: research project for risk assessment. MOAH fraction: Standing Committee on Plants, Animals, Food and Feed Section Novel Food and Toxicological Safety of the Food Chain 19 October 2022

Specific migration of acrylonitrile [CAS: 107-13-1] from a plastic food contact material. The substance is listed as FCM 225 with Ref No. 12100 in European Commission Regulation No 2011/10. According to the regulation, there must be no detectable migration of acrylonitrile to food with a 0.01 mg/kg detection limit.

Specific migration of hexamethylene diisocyanate [CAS: 822-06-0] from a sample or material intended for food contact. The substance is listed under FCM 372 and Ref No. 18640 in European Commission Regulation No 10/2011 on plastic food contact materials. The specific migration limit (SML) of hexamethylene diisocyanate is ND (not detected), which means migration must not be observed with a 0.01 mg/kg detection limit. Note that we also offer an isocyanate testing package for measuring the residual content of hexamethylene diisocyanate and three additional isocyanates.