TOP assay (PFAS precursors)

Total oxidizable precursor (TOP) assay can be used when estimating the presence of PFAS precursors and intermediates by oxidizing them into stable end-products. The analysis can be combined with traditional PFAS analysis methods to obtain additional information.

The following are examples of compounds that can be analyzed:

Abbreviation

Compound

CAS number

PFBA

perfluorobutanoic acid

375-22-4

PFPeA

perfluoropentanoic acid

2706-90-3

PFHxA

perfluorohexanoic acid

307-24-4

PFHpA

perfluoroheptanoic acid

375-85-9

PFOA

perfluorooctanoic acid

335-67-1

PFNA

perfluorononanoic acid

375-95-1

PFDA

perfluorodecanoic acid

335-76-2

PFUnA; PFUdA

perfluoroundecanoic acid

2058-94-8

PFDoA

perfluorododecanoic acid

307-55-1

PFTrDA; PFTriA

perfluorotridecanoic acid

72629-94-8

PFTeA

perfluorotetradecanoic acid

376-06-7

PFHxDA

perfluorohexadecanoic acid

67905-19-5

PFODA

perfluorooctadecanoic acid

16517-11-6

PFBS

perfluorobutanesulfonic acid

375-73-5

PFPeS

perfluoropentanesulfonic acid

2706-91-4

PFHxS

perfluorohexanesulfonic acid

355-46-4

PFHpS

perfluoroheptanesulfonic acid

375-92-8

PFOS

perfluorooctanesulfonic acid

1763-23-1

PFNS

Perfluorononanesulfonic acid

68259-12-1

PFDS

perfluorodecanesulfonic acid

335-77-3

PFUnDS

perfluoroundecanesulfonic acid

749786-16-1

PFDoS

perfluorododecanesulfonic acid

79780-39-5

HFPO-DA (Gen X)

2,3,3,3-Tetrafluoro-2-(heptafluoropropoxy)propanoic acid

13252-13-6

HFPO-TA

perfluoro-2,5-dimethyl-3,6-dioxanonanoic acid

13252-14-7

DONA; ADONA

4,8-dioxa-3H-perfluorononanoic acid

919005-14-4

PFMOPrA

perfluoro-3-methoxypropanoic acid

377-73-1

NFDHA

perfluoro-3,6-dioxaheptanoic acid

151772-58-6

PFMOBA

perfluoro-4-methoxybutanoic acid

863090-89-5

PFecHS

cyclohexanesulfonic acid, 1,2,2,3,3,4,5,5,6,6-decafluoro-4-(1,1,2,2,2-pentafluoroethyl)-, potassium salt (1:1)

335-24-0

3:3 FTCA

2H,2H,3H,3H-perfluorohexanoic acid

356-02-5

5:3 FTCA

2H,2H,3H,3H-perfluorooctanoic acid

914637-49-3

7:3 FTCA

2H,2H,3H,3H-perfluorodecanoic acid

812-70-4

PFEESA

perfluoro(2-ethoxyethane)sulfonic acid

113507-82-7

6:2 Cl-PFESA; 9Cl-PF3ONS

9-chlorohexadecafluoro-3-oxanonane-1-sulfonic acid

756426-58-1

8:2 Cl-PFESA; 11Cl-PF3OUdS

11-chloroeicosafluoro-3-oxaundecane-1-sulfonic acid

763051-92-9

4:2 FTSA; 4:2 FTS

4:2 fluorotelomer sulfonic acid

757124-72-4

6:2 FTSA; 6:2 FTS

6:2 fluorotelomer sulfonic acid

27619-97-2

8:2 FTSA; 8:2 FTS

8:2 fluorotelomer sulfonic acid

39108-34-4

FBSA

perfluorobutane sulfonamide

30334-69-1

FHxSA

perfluorohexanesulfonamide

41997-13-1

FOSA

perfluorooctanesulfonamide

754-91-6

MeFOSA; N-MeFOSA

n-methylperfluorooctanesulfonamide

31506-32-8

EtFOSA; N-EtFOSA

n-ethylperfluorooctanesulfonamide

4151-50-2

MeFOSE

n-methylperfluorooctanesulfonamidoethanol

24448-09-7

EtFOSE

n-ethylperfluorooctanesulfonamidoethanol

1691-99-2

NMeFOSAA; MeFOSAA

n-methylperfluorooctanesulfonamidoacetic acid

2355-31-9

NEtFOSAA; EtFOSAA

n-ethylperfluorooctanesulfonamidoacetic acid

2991-50-6

FOSAA

perfluorooctane sulfonamidoacetic acid

2806-24-8

10:2 FTS

10:2 Fluorotelomer sulfonic acid

108026-35-3

The analysis is suitable for different matrices, such as water and fire-fighting foams.

Contact us for more information and a quote for analyzing your samples.

Required sample quantity
2 x 250 ml of water/liquid or 50 g of solid material in HDPE containers
Detection limit
The reporting limit/LOQ depends on the sample matrix (1–10 ng/L; 1–100 µg/kg)
Available quality systems
Accredited testing laboratory
Device types

Price

Typical price range (Excl. VAT):
250–450 €per sample

We also charge a 97 € service fee per order.

Large batches of samples are eligible for discounts.

Questions? We're happy to help.

Questions? We're happy to help.

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