Zeta potential analysis
Zeta potential is a measure of the electric potential at the interface between a solid particle and a liquid in which it is suspended. Zeta potential analysis is used to estimate the stability of colloidal dispersions, which are widely used in various industries, from pharmaceuticals and food to electronics and mineral processing.
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Zeta potential, also known as electrokinetic potential, measures the “charge of a particle” in a liquid medium. Most often results are given in millivolts.
Zeta potential occurs when particles come in contact with a liquid. The functional groups on the particle surface will react with surrounding liquid, which results in a surface charge of the particle. This charge attracts the accumulation of oppositely charged ions and forms a so-called electronic double layer (DL, EDL). The zeta potential is the sum of the initial surface charge and the accumulated layer charge.
Zeta potential is used to describe the dispersion stability. Typically, low zeta potential indicates instability - aggregation, coagulation, or flocculation of the particles. Instead, high zeta potential indicates feasible stability.
However, several factors including pH, buffer concentration, temperature, and ionic strength influence the zetapotential.
Suitable sample matrices
- Nanoparticles
- Pharmaceuticals
- Colloids
- Polymers
- Emulsions
Ideal uses of zeta potential analysis
- Determine the zeta potential of the particles that are dispersed in a liquid medium.
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Frequently asked questions
Determine the zeta potential of the particles that are dispersed in a liquid medium
Analyse the stability of the particles in liquid medium.
Samples can be in a wet or dry state, since samples are dissolved in liquid media prior to analysis.
Measurlabs offers a variety of laboratory analyses for product developers and quality managers. We perform some of the analyses in our own lab, but mostly we outsource them to carefully selected partner laboratories. This way we can send each sample to the lab that is best suited for the purpose, and offer high-quality analyses with more than a thousand different methods to our clients.
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Samples are usually delivered to our laboratory via courier. Contact us for further details before sending samples.