Glycan profiling (N- and O-linked) of protein samples

Profiling of N- and O-linked glycans from protein samples by Mass Spectrometry. Analysis of N-linked glycans includes PNGase digestion of the proteins to liberate N-glycans, permethylation of N-glycans, and analysis of native and permethylated glycans by Mass Spectrometry. Analysis of O-linked glycans includes Isolation of O-glycopeptides after proteolytic digest of the protein, liberation of O-glycans by reductive β-elimination, permethylation of O-glycans, and analysis of permethylated glycans by Mass Spectrometry. The raw data for profiling is provided as an attachment to the test report.

Biological testingCompositional analysis

Suitable sample matrices

Protein samples (matrix has to be agreed in advance)

Minimum sample amount

100 µg protein per sample

Typical turnaround time

6 weeks after receiving the samples

Quality system

Measurlabs validated method

Device families

MS

Method expert

Mirva Hirvi

Price (VAT 0)

First sample: 2,694 €
Additional samples: 2,415 € per sample